![]() A precise estimate of the difference is not possible, but during interphase, chromatin may be hundreds or even thousands of times less condensed than it is during mitosis. The difference in DNA compaction between interphase and mitosis is dramatic. With very few exceptions, mitosis occupies a much smaller fraction of the cell cycle than interphase. Today, scientists know that Flemming had successfully distinguished chromosomes in the interphase portion of the cell cycle from chromosomes undergoing mitosis, or the portion of the cell cycle during which the nucleus divides (Figure 1). ![]() (We still use the word "chromatin" today, albeit in a more biochemical sense to refer to complexes of nuclear DNA and protein.) Specifically, in some cells, chromatin appeared as an amorphous network, although in other cells, it appeared as threadlike bodies that Flemming named "mitosen." Based on his observations, Flemming had the insight to propose that chromatin could undergo reversible transformations in cells. ![]() In his pioneering studies of mitosis, Flemming noted that the nuclear material, which he named " chromatin" for its ability to take up stains, did not have the same appearance in all cells. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |